C. Roland Wolf

The Cap'n'Collar basic leucine zipper transcription factor Nrf2 (NF-E2 p45-related factor 2) controls both constitutive and inducible expression of intestinal detoxification and glutathione biosynthetic enzymes.

Michael McMahon, Ken Itoh, Masayuki Yamamoto et al. · PubMed · 2001 · 656 citations

Chemoprevention Strategy, Biochemistry, Inducible Expression +15

Cytochrome P450 specificities of alkoxyresorufin O-dealkylation in human and rat liver

M.D. Burke, S. Thompson, Richard Weaver et al. · Biochemical Pharmacology · 1994 · 552 citations

Chemical Biology, Redox Biology, Oxidative Stress +16

Feedback control of AHR signalling regulates intestinal immunity

Chris Schiering, Emma Wincent, Amina Metidji et al. · Nature · 2017 · 521 citations · Full text

Mucosal Immunology, Immunology, Autoimmunity +5

Mutations in APC, Kirsten-ras, and p53—alternative genetic pathways to colorectal cancer

Gillian Smith, Francis A. Carey, Julie Beattie et al. · Proceedings of the National Academy of Sciences · 2002 · 516 citations · Full text

Loss of the Nrf2 transcription factor causes a marked reduction in constitutive and inducible expression of the glutathione S-transferase Gsta1, Gsta2, Gstm1, Gstm2, Gstm3 and Gstm4 genes in the livers of male and female mice

Simon A. Chanas, Qingwu Jiang, Michael McMahon et al. · Biochemical Journal · 2002 · 443 citations · Full text