Yury Kapelyukh

Quantitative Prediction of Human Pregnane X Receptor and Cytochrome P450 3A4 Mediated Drug-Drug Interaction in a Novel Multiple Humanized Mouse Line

Maki Hasegawa, Yury Kapelyukh, Harunobu Tahara et al. · Molecular Pharmacology · 2011 · 85 citations

Medicine, Pharmacology, Biochemical Pharmacology +16

Defining the Contribution of CYP1A1 and CYP1A2 to Drug Metabolism Using Humanized CYP1A1/1A2 and Cyp1a1/Cyp1a2 Knockout Mice

Yury Kapelyukh, Colin J. Henderson, Nico Scheer et al. · Drug Metabolism and Disposition · 2019 · 60 citations · Full text

Medicine, Pharmacology, Toxicology +16

Modeling Human Cytochrome P450 2D6 Metabolism and Drug-Drug Interaction by a Novel Panel of Knockout and Humanized Mouse Lines

Nico Scheer, Yury Kapelyukh, Jillian McEwan et al. · Molecular Pharmacology · 2011 · 56 citations

Medicine, Molecular Biology, Pharmacology +17

Multiple Substrate Binding by Cytochrome P450 3A4: Estimation of the Number of Bound Substrate Molecules

Yury Kapelyukh, Mark J. I. Paine, Jean‐Didier Maréchal et al. · Drug Metabolism and Disposition · 2008 · 55 citations

Medicine, Biochemistry, Pharmacology +17

Generation and Characterization of Novel Cytochrome P450 Cyp2c Gene Cluster Knockout and CYP2C9 Humanized Mouse Lines

Nico Scheer, Yury Kapelyukh, Lynsey R. Chatham et al. · Molecular Pharmacology · 2012 · 55 citations

Medicine, Molecular Biology, Pharmacology +14