Concepedia

A Small-Molecule Oxocarbazate Inhibitor of Human Cathepsin L Blocks Severe Acute Respiratory Syndrome and Ebola Pseudotype Virus Infection into Human Embryonic Kidney 293T cells

Parag P. Shah, Tianhua Wang, Rachel Kaletsky, Michael C. Myers, Jeremy E. Purvis, Huiyan Jing, Donna M. Huryn, Doron C. Greenbaum, Amos B. Smith, Paul Bates,

Molecular Pharmacology · 2010 · 121 citations · 21 references

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21

Inhibitors of cathepsin L prevent severe acute respiratory syndrome coronavirus entry

Graham Simmons, Dhaval N. Gosalia, Andrew J. Rennekamp et al. · Proceedings of the National Academy of Sciences · 2005 · 1.1K citations · Full text

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Evaluation of enzyme inhibitors in drug discovery. A guide for medicinal chemists and pharmacologists.

Robert A. Copeland · PubMed · 2005 · 1.1K citations

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Endosomal Proteolysis of the Ebola Virus Glycoprotein Is Necessary for Infection

Kartik Chandran, Nancy J. Sullivan, Ute Felbor et al. · Science · 2005 · 835 citations · Full text

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Structure of the Ebola virus glycoprotein bound to an antibody from a human survivor

Jeffrey E. Lee, Marnie L. Fusco, Ann J. Hessell et al. · Nature · 2008 · 740 citations · Full text

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Epoxide electrophiles as activity-dependent cysteine protease profiling and discovery tools

Doron C. Greenbaum, Katalin F. Medzihradszky, Alma L. Burlingame et al. · Chemistry & Biology · 2000 · 584 citations · Full text

, , +16