Donna M. Huryn - Concepedia

Author

Donna M. Huryn

Also Known As

D HURYN, D. Huryn, D. M. HURYN, D. M. Huryn, D.M. Huryn, DONNA M. HURYN, Donna Huryn, Donna M Huryn, Donna M. Huryn, Donna M. Huryn

199

Publications

4.9K

Citations

H-Index

101

Concepts

All Affiliations

University of Pittsburgh University of Pennsylvania Princeton University University of California, San Francisco Leidos (United States)

About

Donna M. Huryn is an author at University of Pittsburgh specializing in medicine, pharmacology, and drug discovery.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	25	37	1.9K
2	Biochemistry	20	25	1.5K
3	Natural Sciences	19	24	1.2K
4	Engineering	3	3	111
5	Social Sciences	1	1	109

Donna M. Huryn

Publications

3.1K

Citations

H-Index

Page 1

	Year	Citations
2.3 Å resolution cryo-EM structure of human p97 and mechanism of allosteric inhibition Soojay Banerjee, Alberto Bartesaghi, Alan Merk, Science	2016	353
Structure Property Relationships of Carboxylic Acid Isosteres Pierrik Lassalas, Bryant Gay, Caroline Lasfargeas, Journal of Medicinal Chemistry Combinatorial ChemistryBioorganic ChemistryOrganic ChemistryChemistryChemical Derivative	2016	271
Begacestat (GSI-953): A Novel, Selective Thiophene Sulfonamide Inhibitor of Amyloid Precursor Protein γ-Secretase for the Treatment of Alzheimer’s Disease Robert Martone, Hua Zhou, Kevin Atchison, Journal of Pharmacology and Experimental Therapeutics	2009	157
Select pyrimidinones inhibit the propagation of the malarial parasite, Plasmodium falciparum Annette Chiang, Juan‐Carlos Valderramos, Raghavan Balachandran, Bioorganic & Medicinal Chemistry Select PyrimidinonesBiochemistryAntiparasitic AgentMedicineMalaria	2009	140
Optimization of a Higher Throughput Microsomal Stability Screening Assay for Profiling Drug Discovery Candidates Li Di, Edward H. Kerns, Yan Hong, SLAS DISCOVERY	2003	135
Ferroptosis as a Novel Therapeutic Target for Friedreich’s Ataxia M. Grazia Cotticelli, Shujuan J. Xia, Daniel W. Lin, Journal of Pharmacology and Experimental Therapeutics	2019	133
A Small-Molecule Oxocarbazate Inhibitor of Human Cathepsin L Blocks Severe Acute Respiratory Syndrome and Ebola Pseudotype Virus Infection into Human Embryonic Kidney 293T cells Parag P. Shah, Tianhua Wang, Rachel Kaletsky, Molecular Pharmacology	2010	121
Discovery of Begacestat, a Notch-1-Sparing γ-Secretase Inhibitor for the Treatment of Alzheimer’s Disease Scott C. Mayer, Anthony F. Kreft, Boyd L. Harrison, Journal of Medicinal Chemistry Stable Analogue 10Alzheimer ’Social SciencesNeuroinflammationAlzheimer's Disease	2008	109
Identification of Aminothienopyridazine Inhibitors of Tau Assembly by Quantitative High-Throughput Screening Alex Crowe, Wenwei Huang, Carlo Ballatore, Biochemistry Chemical BiologyMedicinal ChemistryAlzheimer's DiseaseAminothienopyridazine InhibitorsDegenerative Pathology	2009	101
HTS Identifies Novel and Specific Uncompetitive Inhibitors of the Two-Component NS2B-NS3 Proteinase of West Nile Virus Paul A. Johnston, Jennifer Phillips, Tong Ying Shun, Assay and Drug Development Technologies Wnv Ns2b-ns3proSpecific Uncompetitive InhibitorsViral PathogenesisImmunologyMolecular Biology	2007	98

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