Alan Merk

Breaking Cryo-EM Resolution Barriers to Facilitate Drug Discovery

Alan Merk, Alberto Bartesaghi, Soojay Banerjee et al. · Cell · 2016 · 509 citations · Full text

Drug Repositioning, Drug Target, Medicine +4

2.2 Å resolution cryo-EM structure of β-galactosidase in complex with a cell-permeant inhibitor

Alberto Bartesaghi, Alan Merk, Soojay Banerjee et al. · Science · 2015 · 456 citations · Full text

High Resolution, Protein Assembly, Biochemistry +15

2.3 Å resolution cryo-EM structure of human p97 and mechanism of allosteric inhibition

Soojay Banerjee, Alberto Bartesaghi, Alan Merk et al. · Science · 2016 · 353 citations · Full text

Structure of β-galactosidase at 3.2-Å resolution obtained by cryo-electron microscopy

Alberto Bartesaghi, Doreen Matthies, Soojay Banerjee et al. · Proceedings of the National Academy of Sciences · 2014 · 204 citations · Full text

Cryo-EM structure of a dimeric B-Raf:14-3-3 complex reveals asymmetry in the active sites of B-Raf kinases

Yasushi Kondo, Jana Ognjenović, Saikat Banerjee et al. · Science · 2019 · 191 citations · Full text

Active Sites, Kinase Inhibitors, Molecular Biology +16