KRAS codon 61, 146 and BRAF mutations predict resistance to cetuximab plus irinotecan in KRAS codon 12 and 13 wild-type metastatic colorectal cancer - Concepedia

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Publication | Open Access

KRAS codon 61, 146 and BRAF mutations predict resistance to cetuximab plus irinotecan in KRAS codon 12 and 13 wild-type metastatic colorectal cancer

DOI Full Paper Access

557

Citations

24

References

2009

Year

Fotios Loupakis, Annamaria Ruzzo, Chiara Cremolini, Bruno Vincenzi, Lisa Salvatore, Daniele Santini, Gianluca Masi, I. Stasi, Emanuele Canestrari, Eliana Rulli,

British Journal of Cancer

Abstract

Assessing KRAS codons 61/146 and BRAF V600E mutations might help optimising the selection of the candidate patients to receive anti-EGFR moAbs.

References

	Year	Citations

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