Concepedia

2-Aroylquinoline-5,8-diones as potent anticancer agents displaying tubulin and heat shock protein 90 (HSP90) inhibition

Kunal Nepali, Sunil Kumar, Hsiang-Ling Huang, Fei-Chiao Kuo, Ching‐Chuan Kuo, Teng‐Kuang Yeh, Yu-Hsuan Li, Jang‐Yang Chang, Jing‐Ping Liou, Hsueh‐Yun Lee

Organic & Biomolecular Chemistry · 2015 · 13 citations · 23 references

DOI

Concepts

Abstract

Correction for '2-Aroylquinoline-5,8-diones as potent anticancer agents displaying tubulin and heat shock protein 90 (HSP90) inhibition' by Kunal Nepali et al., Org. Biomol. Chem., 2016, 14, 716-723.

References

23

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.9K citations

, , +14

Inhibition of heat shock protein HSP90-pp60v-src heteroprotein complex formation by benzoquinone ansamycins: essential role for stress proteins in oncogenic transformation.

Luke Whitesell, Edward G. Mimnaugh, B. de Costa et al. · Proceedings of the National Academy of Sciences · 1994 · 1.4K citations

, , +14

Epothilones, a new class of microtubule-stabilizing agents with a taxol-like mechanism of action

Suzanne B. Buck, Sam F. Victory, Richard H. Himes et al. · 1998 · 983 citations

, , +10

Modulation of Akt kinase activity by binding to Hsp90

Saori Sato, Naoya Fujita, Takashi Tsuruo · Proceedings of the National Academy of Sciences · 2000 · 959 citations · Full text

, , +17

Preclinical pharmacologic evaluation of geldanamycin as an antitumor agent

Jeffrey G. Supko, Robert L. Hickman, Michael R. Grever et al. · Cancer Chemotherapy and Pharmacology · 1995 · 496 citations

, , +9