Concepedia
Journal of Pharmaceutical Sciences · 2010 · 51 citations · 23 references
Tissue BindingUnbound VolumeEngineeringMedical BiophysicsBioanalysisArtificial Membrane-binding MeasurementsAnalytical ChemistryBiomedical EngineeringClinical ChemistryChromatographic AnalysisMedicineBiophysicsChromatographyDrug Analysis
23
Physiochemical drug properties associated with in vivo toxicological outcomes
Jason D. Hughes, Julian Blagg, David A. Price et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 945 citations
Preclinical Drug Evaluation, Medicine, Toxicology +5
Physiologically Based Pharmacokinetic Modeling 1: Predicting the Tissue Distribution of Moderate-to-Strong Bases
Trudy Rodgers, David E. Leahy, Malcolm Rowland · Journal of Pharmaceutical Sciences · 2005 · 765 citations
Pharmacokinetic Modeling, Medicine, Physiology +8
A Comparison of Physiochemical Property Profiles of Development and Marketed Oral Drugs
Mark C. Wenlock, Rupert P. Austin, Patrick Barton et al. · Journal of Medicinal Chemistry · 2003 · 530 citations
Molecular Pharmacology, Rigorous Selection Pressures, Physiochemical Property Profiles +13
Mechanistic Approaches to Volume of Distribution Predictions: Understanding the Processes
Trudy Rodgers, Malcolm Rowland · Pharmaceutical Research · 2007 · 409 citations
Probabilistic Forecasting, Engineering, Density Estimation +12
The importance of plasma protein binding in drug discovery
George L. Trainor · Expert Opinion on Drug Discovery · 2007 · 336 citations
Drug Target, Quantitative Pharmacology, Cellular Pharmacology +18