Concepedia

Drug Tissue Binding

Drug Tissue Binding is a pharmacokinetic process in which a drug reversibly associates with components of bodily tissues, distinguishing it from plasma protein binding by involving extracellular matrix, cellular structures, or specific tissue-resident molecules that sequester the drug outside the vascular compartment.

220

Publications

9.7K

Citations

732

Authors

238

Institutions

Publications per year

2017–2026

27

Parents

Publications

220

Influence of nonspecific brain and plasma binding on CNS exposure: implications for rational drug discovery

J. Cory Kalvass, Tristan S. Maurer · Biopharmaceutics & Drug Disposition · 2002 · 415 citations

, , +15

Arterial Paclitaxel Distribution and Deposition

Christopher J. Creel, Mark A. Lovich, Elazer R. Edelman · Circulation Research · 2000 · 275 citations

, , +13

Age differences in drug binding by plasma proteins: Studies on human foetuses, neonates and adults

M. Ehrnebo, Stig Agurell, Birgitta Jalling et al. · European Journal of Clinical Pharmacology · 1971 · 266 citations

, , +14

Valproic Acid

Rick D. Davis, David H. Peters, Donna McTavish · Drugs · 1994 · 238 citations

, , +14

Relationships between hydrophobicity, reactivity, accumulation and peripheral nerve toxicity of a series of platinum drugs

D Screnci, Mark J. McKeage, Peter Galettis et al. · British Journal of Cancer · 2000 · 175 citations · Full text

, , +17

1–5 of 220

Authors

732

  1. MA
    Mark A. Lovich

    St. Elizabeth's Medical Center, United States

    4 publications · 372 citations

    4

    h-index

  2. WJ
    William J. Jusko

    University at Buffalo, State University of New York, United States

    4 publications · 84 citations

    4

    h-index

  3. HK
    Herbert Kurz

    Medical University of Vienna, Austria

    4 publications · 131 citations

    4

    h-index

  4. KV
    Klára Valkó

    GlaxoSmithKline (United Kingdom), United Kingdom

    4 publications · 136 citations

    4

    h-index

  5. ER
    Elazer R. Edelman

    Massachusetts Institute of Technology, United States

    4 publications · 372 citations

    4

    h-index

1–5 of 732

Institutions

238

  1. University at Buffalo, State University of New York

    Buffalo, United States

    8 h-index

    19 publications

    843 citations

  2. AstraZeneca (Sweden)

    Södertälje, Sweden

    5 h-index

    12 publications

    1.2K citations

  3. University of Minnesota

    Minneapolis, United States

    5 h-index

    11 publications

    823 citations

  4. Pfizer (United States)

    New York, United States

    4 h-index

    12 publications

    1.2K citations

  5. Uppsala University

    Uppsala, Sweden

    4 h-index

    14 publications

    446 citations

  6. University of Washington

    Seattle, United States

    4 h-index

    7 publications

    412 citations

  7. University of Wisconsin–Madison

    Madison, United States

    3 h-index

    7 publications

    138 citations

  8. University of Manchester

    Manchester, United Kingdom

    3 h-index

    3 publications

    57 citations

1–8 of 238

Venues

  1. PubMed

    Repository · 19 publications · 715 citations

    14

    h-index

  2. 12

    h-index

  3. Drug Metabolism and Disposition

    11 publications · 422 citations

    10

    h-index

  4. Journal of Pharmaceutical Sciences

    9 publications · 333 citations

    9

    h-index

  5. European Journal of Clinical Pharmacology

    7 publications · 559 citations

    7

    h-index

1–5