Concepedia

The human polo-like kinase, PLK, regulates cdc2/cyclin B through phosphorylation and activation of the cdc25C phosphatase

Amy Roshak, Elizabeth A. Capper, Christina S. Imburgia, James A. Fornwald, Gilbert Scott, Lisa A. Marshall

Cellular Signalling · 2000 · 214 citations · 16 references

DOI

Concepts

References

16

Phosphorylation and activation of human cdc25‐C by cdc2‐‐cyclin B and its involvement in the self‐amplification of MPF at mitosis.

Ingrid Hoffmann, Paul R. Clarke, María Jesús Marcote et al. · The EMBO Journal · 1993 · 677 citations

, , +14

Myt1: A Membrane-Associated Inhibitory Kinase That Phosphorylates Cdc2 on Both Threonine-14 and Tyrosine-15

Paul R. Mueller, Thomas R. Coleman, Akiko Kumagai et al. · Science · 1995 · 675 citations

, , +16

<i>Polo</i>, a mitotic mutant of <i>Drosophila</i> displaying abnormal spindle poles

Cláudio E. Sunkel, David M. Glover · Journal of Cell Science · 1988 · 561 citations

, , +17

The cdc25 protein controls tyrosine dephosphorylation of the cdc2 protein in a cell-free system

Akiko Kumagai, William G. Dunphy · Cell · 1991 · 506 citations

, , +15

Purification and Molecular Cloning of Plx1, a Cdc25-Regulatory Kinase from <b> <i>Xenopus</i> </b> Egg Extracts

Akiko Kumagai, William G. Dunphy · Science · 1996 · 502 citations

, , +17