Concepedia

Cdc25 Phosphatases

Cdc25 Phosphatases is a family of dual-specificity protein phosphatases that function as key regulatory enzymes in cell cycle progression by specifically dephosphorylating cyclin-dependent kinases at inhibitory phosphorylation sites to promote cell cycle transitions.

451

Publications

38.4K

Citations

1.8K

Authors

538

Institutions

Publications per year

2017–2026

37

Variants

Cdc25 Phosphatase

Parents

Publications

451

Conservation of the Chk1 Checkpoint Pathway in Mammals: Linkage of DNA Damage to Cdk Regulation Through Cdc25

Yolanda Sánchez, Calvin Wong, Richard S. Thoma et al. · Science · 1997 · 1.3K citations

, , +17

cdc25 is a specific tyrosine phosphatase that directly activates p34cdc2

Jean Gautier, Mark J. Solomon, Robert N. Booher et al. · Cell · 1991 · 850 citations

, , +9

Cdc25 cell-cycle phosphatase as a target of c-myc

Konstantin Galaktionov, Xiaocun Chen, David Beach · Nature · 1996 · 694 citations

, , +12

Aberrant Cdk5 Activation by p25 Triggers Pathological Events Leading to Neurodegeneration and Neurofibrillary Tangles

Jonathan C. Cruz, Huang-Chun Tseng, Joseph Goldman et al. · Neuron · 2003 · 613 citations · Full text

, , +12

The cdc25 protein contains an intrinsic phosphatase activity

William G. Dunphy, Akiko Kumagai · Cell · 1991 · 595 citations

, , +10

1–5 of 451

Authors

1.8K

  1. BD
    Bernard Ducommun

    Centre National de la Recherche Scientifique, France

    37 publications · 2K citations

    27

    h-index

  2. JS
    John S. Lazo

    University of Pittsburgh, United States

    23 publications · 1.4K citations

    20

    h-index

  3. HP
    Helen Piwnica‐Worms

    Howard Hughes Medical Institute, United States

    15 publications · 4K citations

    15

    h-index

  4. IH
    Ingrid Hoffmann

    German Cancer Research Center, Germany

    14 publications · 2.1K citations

    14

    h-index

  5. BI
    Brian I. Carr

    University of Pittsburgh, United States

    11 publications · 496 citations

    11

    h-index

1–5 of 1.8K

Institutions

538

  1. Centre National de la Recherche Scientifique

    Paris, France

    34 h-index

    244 publications

    13.4K citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    25 h-index

    62 publications

    24K citations

  3. Laboratoire de Biologie Cellulaire et Moléculaire du Contrôle de la Prolifération

    Toulouse, France

    25 h-index

    108 publications

    7.1K citations

  4. Université Toulouse III - Paul Sabatier

    Toulouse, France

    25 h-index

    123 publications

    8.1K citations

  5. University of Pittsburgh

    Pittsburgh, United States

    21 h-index

    84 publications

    7.1K citations

  6. Duke Medical Center

    Durham, United States

    15 h-index

    61 publications

    5K citations

  7. Duke University Hospital

    Durham, United States

    14 h-index

    51 publications

    4.6K citations

  8. German Cancer Research Center

    Heidelberg, Germany

    12 h-index

    33 publications

    3.7K citations

1–8 of 538

Venues

  1. Journal of Biological Chemistry

    JBC · 27 publications · 2.6K citations

    23

    h-index

  2. Oncogene

    19 publications · 1.3K citations

    19

    h-index

  3. Cell Cycle

    22 publications · 1.1K citations

    19

    h-index

  4. PubMed

    Repository · 18 publications · 1.3K citations

    17

    h-index

  5. Molecular Biology of the Cell

    MBC · 17 publications · 1.7K citations

    16

    h-index

1–5