Jonathan C. Cruz - Concepedia

Author

Jonathan C. Cruz

Merck & Co., Inc., Rahway, NJ, USA (United States)

Also Known As

Cruz, J. C. Santos, J Cruz, J. Cruz, Jonathan C Cruz, Jonathan C. Cruz, Jonathan Cruz

Publications

2.8K

Citations

H-Index

Concepts

All Affiliations

Merck & Co., Inc., Rahway, NJ, USA (United States)Dartmouth College Harvard University Howard Hughes Medical Institute

About

Jonathan C. Cruz is an author at Merck & Co., Inc., Rahway, NJ, USA (United States) specializing in biochemistry, medicine, and natural sciences.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Biochemistry	14	14	717
2	Medicine	13	13	1.2K
3	Natural Sciences	12	12	670
4	Chemical Biology	8	8	400
5	Cell Biology	2	2	670

Jonathan C. Cruz

Publications

1.9K

Citations

H-Index

Page 1

	Year	Citations
Aberrant Cdk5 Activation by p25 Triggers Pathological Events Leading to Neurodegeneration and Neurofibrillary Tangles Jonathan C. Cruz, Huang-Chun Tseng, Joseph Goldman, Neuron Neurodegenerative DiseasesSignal TransductionSignaling PathwayReceptor Tyrosine KinaseNeurofibrillary Tangles	2003	606
p25/Cyclin-Dependent Kinase 5 Induces Production and Intraneuronal Accumulation of Amyloid β<i>In Vivo</i> Jonathan C. Cruz, Do‐Hoon Kim, Lily Y. Moy, Journal of Neuroscience	2006	202
Exploration of the internal cavity of histone deacetylase (HDAC) with selective HDAC1/HDAC2 inhibitors (SHI-1:2) Joey L. Methot, Prasun K. Chakravarty, Mélissa Chénard, Bioorganic & Medicinal Chemistry Letters Histone ModificationsChromatinMedicinal ChemistrySelective Hdac1/hdac2 InhibitorsBiochemistry	2007	185
Role of Niemann-Pick Type C1 Protein in Intracellular Trafficking of Low Density Lipoprotein-derived Cholesterol Jonathan C. Cruz, Shigeki Sugii, Chunjiang Yu, Journal of Biological Chemistry	2000	177
Recombinant Acyl-CoA:cholesterol Acyltransferase-1 (ACAT-1) Purified to Essential Homogeneity Utilizes Cholesterol in Mixed Micelles or in Vesicles in a Highly Cooperative Manner Catherine C.Y. Chang, Chi‐Yu Gregory Lee, Ellen T. Chang, Journal of Biological Chemistry OxysterolCellular EnzymologyBiochemistryNatural SciencesMolecular Biology	1998	133
Fate of Endogenously Synthesized Cholesterol in Niemann-Pick Type C1 Cells Jonathan C. Cruz, Ta‐Yuan Chang Journal of Biological Chemistry	2000	94
Mammalian Retina: Associational Nerve Cells in Ganglion Cell Layer A. Gallego, Jonathan C. Cruz Science Ganglion CellCellular NeurobiologyRetinaEpendymaOphthalmology	1965	70
Passage of serum-destined proteins through the Golgi apparatus of rat liver. An examination of heavy and light Golgi fractions. John Bergeron, D Borts, Jonathan C. Cruz The Journal of Cell Biology Protein SecretionProtein PurificationLiver Golgi FractionsBioanalysisHepatotoxicity	1978	64
SAR profiles of spirocyclic nicotinamide derived selective HDAC1/HDAC2 inhibitors (SHI-1:2) Joey L. Methot, Christopher L. Hamblett, Dawn M. Mampreian, Bioorganic & Medicinal Chemistry Letters Medicinal ChemistryPharmaceutical ScienceSar ProfilesBiochemistryMedicine	2008	44
The discovery of 6-amino nicotinamides as potent and selective histone deacetylase inhibitors Christopher L. Hamblett, Joey L. Methot, Dawn M. Mampreian, Bioorganic & Medicinal Chemistry Letters Medicinal ChemistryBiochemistryMedicineNatural SciencesRational Drug Design	2007	43

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