Jonathan C. Cruz

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Publications

Citations

1.9K

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Active since

1965

Affiliations

Merck & Co., Inc., Rahway, NJ, USA (United States)(Current)

Dartmouth College

Harvard University

Howard Hughes Medical Institute

United States Military Academy

Jonathan C. Cruz is an author at Merck & Co., Inc., Rahway, NJ, USA (United States) specializing in life sciences, enzyme inhibition, and pharmacology.

Publications per year

1965–2015

Publications

Aberrant Cdk5 Activation by p25 Triggers Pathological Events Leading to Neurodegeneration and Neurofibrillary Tangles

Jonathan C. Cruz, Huang-Chun Tseng, Joseph Goldman et al. · Neuron · 2003 · 613 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +12

p25/Cyclin-Dependent Kinase 5 Induces Production and Intraneuronal Accumulation of Amyloid β<i>In Vivo</i>

Jonathan C. Cruz, Do‐Hoon Kim, Lily Y. Moy et al. · Journal of Neuroscience · 2006 · 203 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Exploration of the internal cavity of histone deacetylase (HDAC) with selective HDAC1/HDAC2 inhibitors (SHI-1:2)

Joey L. Methot, Prasun K. Chakravarty, Mélissa Chénard et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 187 citations · Full text

Life Sciences, Biochemistry, Medicinal Chemistry +10

Role of Niemann-Pick Type C1 Protein in Intracellular Trafficking of Low Density Lipoprotein-derived Cholesterol

Jonathan C. Cruz, Shigeki Sugii, Chunjiang Yu et al. · Journal of Biological Chemistry · 2000 · 179 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Recombinant Acyl-CoA:cholesterol Acyltransferase-1 (ACAT-1) Purified to Essential Homogeneity Utilizes Cholesterol in Mixed Micelles or in Vesicles in a Highly Cooperative Manner

Catherine C.Y. Chang, Chi‐Yu Gregory Lee, Ellen T. Chang et al. · Journal of Biological Chemistry · 1998 · 136 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

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