Concepedia

Crosstalk Between Reticular Adherens Junctions and Platelet Endothelial Cell Adhesion Molecule-1 Regulates Endothelial Barrier Function

Laura Fernández‐Martín, Beatriz Marcos‐Ramiro, Carolina L. Bigarella, Mariona Graupera, Robert J. Cain, Natalia Reglero-Real, Anaïs Jiménez-Reinoso, Eva Cernuda‐Morollón, Isabel Correas, Susan Cox,

Arteriosclerosis Thrombosis and Vascular Biology · 2012 · 74 citations · 45 references

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Abstract

We propose that reticular AJ act coordinately with PECAM-1 to maintain endothelial barrier function in regions of low actomyosin-mediated tension. Selective disruption of reticular AJ contributes to permeability increase in response to tumor necrosis factor-α.

References

45

Control of β-Catenin Phosphorylation/Degradation by a Dual-Kinase Mechanism

Chunming Liu, Yiming Li, Mikhail A. Semenov et al. · Cell · 2002 · 2.1K citations · Full text

, , +6

Permanent cell line expressing human factor VIII-related antigen established by hybridization.

C J Edgell, C. McDonald, John B. Graham · Proceedings of the National Academy of Sciences · 1983 · 1.5K citations · Full text

, , +16

PECAM-1 is required for transendothelial migration of leukocytes.

William A. Müller, S A Weigl, Xiaohui Deng et al. · The Journal of Experimental Medicine · 1993 · 1.1K citations · Full text

, , +15

Deconstructing the Cadherin-Catenin-Actin Complex

Soichiro Yamada, Sabine Pokutta, Frauke Drees et al. · Cell · 2005 · 992 citations · Full text

, , +7

α-Catenin as a tension transducer that induces adherens junction development

Shigenobu Yonemura, Yuko Wada, Toshiyuki Watanabe et al. · Nature Cell Biology · 2010 · 972 citations

, , +5