Concepedia

Phosphorylation by Casein Kinase I Promotes the Turnover of the Mdm2 Oncoprotein via the SCFβ-TRCP Ubiquitin Ligase

Hiroyuki Inuzuka, Alan Tseng, Daming Gao, Bo Zhai, Qing Zhang, Shavali Shaik, Lixin Wan, Xiaolu L. Ang, Caroline S. Mock, Haoqiang Yin,

Cancer Cell · 2010 · 203 citations · 43 references

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43

WAF1, a potential mediator of p53 tumor suppression

Wafik S. El‐Deiry, Takashi Tokino, Victor E. Velculescu et al. · Cell · 1993 · 8.4K citations

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Mdm2 promotes the rapid degradation of p53

Ygal Haupt, Ruth Maya, Anat Kazaz et al. · Nature · 1997 · 4.5K citations

, , +10

Requirement for p53 and p21 to Sustain G <sub>2</sub> Arrest After DNA Damage

Fred Bunz, Annie Dutriaux, Christoph Lengauer et al. · Science · 1998 · 2.8K citations

, , +17

Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53

Roberto Montes de Oca Luna, Daniel S. Wagner, Guillermina Lozano · Nature · 1995 · 1.4K citations

, , +12

DNA Damage-Induced Activation of p53 by the Checkpoint Kinase Chk2

Atsushi Hirao, Young‐Yun Kong, Shuhei Matsuoka et al. · Science · 2000 · 1.3K citations

, , +17