Oct‐3/4 regulates stem cell identity and cell fate decisions by modulating Wnt/β‐catenin signalling

Core Transcriptional Regulatory Circuitry in Human Embryonic Stem Cells

Laurie A. Boyer, Tong Ihn Lee, Megan F. Cole et al. · Cell · 2005 · 4.5K citations · Full text

Life Sciences, Cell Biology, Developmental Biology +14

Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells

Hitoshi Niwa, Jun‐ichi Miyazaki, Austin Smith · Nature Genetics · 2000 · 3.6K citations

Life Sciences, Cell Biology, Developmental Biology +13

Formation of Pluripotent Stem Cells in the Mammalian Embryo Depends on the POU Transcription Factor Oct4

Jennifer Nichols, Branko Zevnik, Konstantinos Anastassiadis et al. · Cell · 1998 · 3.4K citations · Full text

Life Sciences, Cell Biology, Developmental Biology +11

Constitutive Transcriptional Activation by a β-Catenin-Tcf Complex in APC ^−/− Colon Carcinoma

Vladimír Kořínek, Nick Barker, Patrice J. Morin et al. · Science · 1997 · 3.3K citations

Medicine, Cancer Biology, Molecular Genetics +17

Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor

Noboru Sato, Laurent Meijer, Léandros Skaltsounis et al. · Nature Medicine · 2003 · 2.1K citations

Life Sciences, Cell Biology, Developmental Biology +14