Concepedia

Publication | Open Access

β-Cell Hyperplasia Induced by Hepatic Insulin Resistance

DOIFull Paper Access

70

Citations

34

References

2009

Year

Óscar Escribano, Carlos Guillén, Carmen Nevado, Almudena Gómez‐Hernández, C. Ronald Kahn, Manuel Benito
Diabetes

Abstract

Our studies of iLIRKO mice suggest a liver-pancreas endocrine axis in which IGF-1 functions as a liver-derived growth factor to promote compensatory pancreatic islet hyperplasia through IR-A.

References

YearCitations

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