Concepedia

Microwave promoted synthesis of functionalized 2-aminothiazoles

George W. Kabalka, Arjun R. Mereddy

Tetrahedron Letters · 2006 · 89 citations · 15 references

DOI

Concepts

References

15

Structure-activity relationships of a series of 2-amino-4-thiazole-containing renin inhibitors

William C. Patt, Harriet W. Hamilton, Michael D. Taylor et al. · Journal of Medicinal Chemistry · 1992 · 373 citations · Full text

, , +15

<i>N</i>-(Cycloalkylamino)acyl-2-aminothiazole Inhibitors of Cyclin-Dependent Kinase 2. <i>N</i>-[5-[[[5-(1,1-Dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-4- piperidinecarboxamide (BMS-387032), a Highly Efficacious and Selective Antitumor Agent

Raj N. Misra, Hai‐Yun Xiao, Kyoung S. Kim et al. · Journal of Medicinal Chemistry · 2004 · 251 citations · Full text

, , +7

<i>seco</i>-Cyclothialidines:  New Concise Synthesis, Inhibitory Activity toward Bacterial and Human DNA Topoisomerases, and Antibacterial Properties

Joachim Rudolph, Heidi Theis, Roman Hanke et al. · Journal of Medicinal Chemistry · 2001 · 196 citations · Full text

, , +11

Discovery of Aminothiazole Inhibitors of Cyclin-Dependent Kinase 2:  Synthesis, X-ray Crystallographic Analysis, and Biological Activities

Kyoung Soon Kim, S. David Kimball, Raj N. Misra et al. · Journal of Medicinal Chemistry · 2002 · 157 citations · Full text

, , +14

Solid-Phase Synthesis of 2-Aminothiazoles

Patrick C. Kearney, Mónica Fernández, John A. Flygare · The Journal of Organic Chemistry · 1998 · 148 citations

, , +6