Progressive Increase in Point Mutations Associated with Chloroquine Resistance in<i>Plasmodium falciparum</i>Isolates from India

Pooja Mittra, Sumiti Vinayak, Hina Chandawat, Neeru Singh, Sukla Biswas, Vas Dev, Ashwani Kumar, Musharraf A. Ansari, Yagya D. Sharma

The Journal of Infectious Diseases · 2006 · 60 citations · 17 references

DOIFull text

Open access

Abstract

There was a temporal increase in the number of pfcrt and pfmdr1 2-loci mutations, and this led to the higher level of chloroquine resistance. This is a cause for concern for the antimalarial drug policy in India.

References

17