New hospital disinfection processes for both conventional and prion infectious agents compatible with thermosensitive medical equipment

A new variant of Creutzfeldt-Jakob disease in the UK

Robert Will, James W. Ironside, Martin Zeidler et al. · The Lancet · 1996 · 2.7K citations

Creutzfeldt-jakob Disease, Neurological Disorder, New Variant +6

The cellular prion protein binds copper in vivo

David R. Brown, Kefeng Qin, Jochen Herms et al. · Nature · 1997 · 1.3K citations

Biochemistry, Natural Sciences, Metalloprotein +5

Human spongiform encephalopathy: The national institutes of health series of 300 cases of experimentally transmitted disease

Paul S. Brown, Clarence J. Gibbs, Pamela Rodgers‐Johnson et al. · Annals of Neurology · 1994 · 816 citations

Tissue distribution of protease resistant prion protein in variant Creutzfeldt-Jakob disease using a highly sensitive immunoblotting assay

Sarah Joiner, T. Campbell, Melanie Desbruslais et al. · The Lancet · 2001 · 688 citations

Autoimmune Disease, Creutzfeldt-jakob Disease, Medicine +8

Strain-specific prion-protein conformation determined by metal ions

Jonathan D. F. Wadsworth, Andrew F. Hill, Susan Joiner et al. · Nature Cell Biology · 1999 · 294 citations

Metal Ions, Biochemistry, Protein Folding +7