Concepedia

Time course-changes in phosphatidylcholine profile during oxidative modification of low-density lipoprotein

Naoko Sasabe, Yuka Keyamura, Takashi Obama, Nozomi Inoue, Yukihiro Masuko, Yu Igarashi, Toshihiro Aiuchi, Rina Kato, Tomohiro Yamaguchi, Hiroshi Kuwata,

Lipids in Health and Disease · 2014 · 28 citations · 38 references

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Abstract

These results suggest that lysoPC species are the major products and PAF-AH activity is crucial for lysoPC generation during oxidation of LDL. The oxPC species accumulated are limited when LDL is oxidized with copper ion in vitro.

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