Presymptomatic DNA testing and prophylactic surgery in families with a BRCA1 or BRCA2 mutation

A Strong Candidate for the Breast and Ovarian Cancer Susceptibility Gene <i>BRCA1</i>

Yoshio Miki, Jeffrey Swensen, Donna Shattuck-Eidens et al. · Science · 1994 · 6.1K citations

Life Sciences, Genetics, Molecular Genetics +17

Tamoxifen for Prevention of Breast Cancer: Report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study

Bernard Fisher, Joseph P. Costantino, D. Lawrence Wickerham et al. · JNCI Journal of the National Cancer Institute · 1998 · 5.5K citations · Full text

Medicine, Oncology, Preventive Medicine +15

Identification of the breast cancer susceptibility gene BRCA2

Richard Wooster, Graham R. Bignell, Jonathan Lancaster et al. · Nature · 1995 · 3.7K citations

Medicine, Genetics, Molecular Genetics +9

Genetic Heterogeneity and Penetrance Analysis of the BRCA1 and BRCA2 Genes in Breast Cancer Families

Deborah Ford, Douglas F. Easton, Michael R. Stratton et al. · The American Journal of Human Genetics · 1998 · 3K citations · Full text

Life Sciences, Genetics, Oncology +17

The Risk of Cancer Associated with Specific Mutations of<i>BRCA1</i>and<i>BRCA2</i>among Ashkenazi Jews

Jeffery P. Struewing, Patricia Hartge, Sholom Wacholder et al. · New England Journal of Medicine · 1997 · 2.3K citations · Full text

Medicine, Genetics, Molecular Genetics +17