Concepedia

Brca2 Mutation Testing

BRCA2 Mutation Testing is a molecular diagnostic assay that identifies pathogenic germline variants in the BRCA2 gene, distinguishing it from other genetic tests by its specific focus on mutations associated with hereditary breast and ovarian cancer susceptibility.

335

Publications

21.9K

Citations

2.3K

Authors

735

Institutions

Publications per year

2017–2026

89

Parents

Publications

335

Spectrum of Mutations in BRCA1, BRCA2, CHEK2, and TP53 in Families at High Risk of Breast Cancer

Tom Walsh, Silvia Casadei, Kathryn Hale Coats et al. · JAMA · 2006 · 666 citations

, , +17

BRCAPRO Validation, Sensitivity of Genetic Testing of <i>BRCA1/BRCA2</i>, and Prevalence of Other Breast Cancer Susceptibility Genes

Donald A. Berry, Edwin S. Iversen, Daníel F. Guðbjartsson et al. · Journal of Clinical Oncology · 2002 · 506 citations · Full text

, , +17

Detection of inherited mutations for breast and ovarian cancer using genomic capture and massively parallel sequencing

Tom Walsh, Ming K. Lee, Silvia Casadei et al. · Proceedings of the National Academy of Sciences · 2010 · 491 citations

, , +17

BRCA2 is a moderate penetrance gene contributing to young-onset prostate cancer: implications for genetic testing in prostate cancer patients

Zsofia Kote‐Jarai, Daniel Leongamornlert, Edward J. Saunders et al. · British Journal of Cancer · 2011 · 400 citations · Full text

, , +17

Integrated Evaluation of DNA Sequence Variants of Unknown Clinical Significance: Application to BRCA1 and BRCA2

Douglas F. Easton, Amie M. Deffenbaugh, Álvaro N.A. Monteiro et al. · The American Journal of Human Genetics · 2004 · 385 citations · Full text

, , +14

1–5 of 335

Authors

2.3K

  1. SA
    Steven A. Narod

    University of Toronto, Canada

    24 publications · 1.8K citations

    18

    h-index

  2. DG
    D. Gareth Evans

    University of Manchester, United Kingdom

    12 publications · 813 citations

    12

    h-index

  3. KM
    Kelly Metcalfe

    University of Toronto, Canada

    9 publications · 752 citations

    9

    h-index

  4. JL
    John L. Hopper

    The University of Melbourne, Australia

    8 publications · 792 citations

    8

    h-index

  5. TP
    Tuya Pal

    Moffitt Cancer Center, United States

    7 publications · 437 citations

    7

    h-index

1–5 of 2.3K

Institutions

735

  1. Women's College Hospital

    Toronto, Canada

    18 h-index

    77 publications

    5.4K citations

  2. University of Toronto

    Toronto, Canada

    18 h-index

    64 publications

    4.8K citations

  3. Dana-Farber Cancer Institute

    Boston, United States

    11 h-index

    54 publications

    4K citations

  4. University of Pennsylvania

    Philadelphia, United States

    11 h-index

    45 publications

    4.9K citations

  5. Cancer Genetics (United States)

    Rutherford, United States

    11 h-index

    33 publications

    3.3K citations

  6. Princess Margaret Cancer Centre

    Toronto, Canada

    11 h-index

    17 publications

    788 citations

  7. Institute of Cancer Research

    London, United Kingdom

    10 h-index

    52 publications

    10.7K citations

  8. The University of Melbourne

    Melbourne, Australia

    9 h-index

    32 publications

    2.5K citations

1–8 of 735

Venues

  1. Journal of Clinical Oncology

    16 publications · 2.6K citations

    16

    h-index

  2. PubMed

    Repository · 18 publications · 1.7K citations

    15

    h-index

  3. Breast Cancer Research and Treatment

    18 publications · 868 citations

    15

    h-index

  4. Clinical Genetics

    13 publications · 413 citations

    13

    h-index

  5. British Journal of Cancer

    BJC · 10 publications · 1.2K citations

    11

    h-index

1–5