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Human Hsp70 Disaggregase Reverses Parkinson’s-Linked α-Synuclein Amyloid Fibrils

Xuechao Gao, Marta Carroni, Carmen Nussbaum‐Krammer, Axel Mogk, Nadinath B. Nillegoda, Anna Szlachcic, D. Lys Guilbride, Helen R. Saibil, Matthias P. Mayer, Bernd Bukau

Molecular Cell · 2015 · 420 citations · 21 references

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21

EGCG remodels mature α-synuclein and amyloid-β fibrils and reduces cellular toxicity

Jan Bieschke, Jenny Russ, Ralf P. Friedrich et al. · Proceedings of the National Academy of Sciences · 2010 · 1K citations · Full text

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The fold of α-synuclein fibrils

Marçal Vilar, Hui‐Ting Chou, Thorsten Lührs et al. · Proceedings of the National Academy of Sciences · 2008 · 553 citations · Full text

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Hsp104 Catalyzes Formation and Elimination of Self-Replicating Sup35 Prion Conformers

James Shorter, Susan Lindquist · Science · 2004 · 475 citations

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C. elegans Model Identifies Genetic Modifiers of α-Synuclein Inclusion Formation During Aging

Tjakko J. van Ham, Karen L. Thijssen, Rainer Breitling et al. · PLoS Genetics · 2008 · 426 citations · Full text

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Structure and Dynamics of the ATP-Bound Open Conformation of Hsp70 Chaperones

Roman Kityk, Jürgen Kopp, Irmgard Sinning et al. · Molecular Cell · 2012 · 401 citations · Full text

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