Carmen Nussbaum‐Krammer

Human Hsp70 Disaggregase Reverses Parkinson’s-Linked α-Synuclein Amyloid Fibrils

Xuechao Gao, Marta Carroni, Carmen Nussbaum‐Krammer et al. · Molecular Cell · 2015 · 408 citations · Full text

Neurodegenerative Diseases, Molecular Biology, Degenerative Pathology +4

Investigating the Spreading and Toxicity of Prion-like Proteins Using the Metazoan Model Organism <em>C. elegans</em>

Carmen Nussbaum‐Krammer, Mário F. Neto, Renée M. Brielmann et al. · Journal of Visualized Experiments · 2015 · 187 citations

Biology, Protein Function, Amyotrophic Lateral Sclerosis +15

Disassembly of Tau fibrils by the human Hsp70 disaggregation machinery generates small seeding-competent species

Eliana Nachman, Anne S. Wentink, Karine Madiona et al. · Journal of Biological Chemistry · 2020 · 161 citations · Full text

Proteotoxic stress and ageing triggers the loss of redox homeostasis across cellular compartments

Janine Kirstein, Daisuke Morito, Taichi Kakihana et al. · The EMBO Journal · 2015 · 90 citations · Full text

Inflammation, Reductive Stress, Aging +13

The HSP110/HSP70 disaggregation system generates spreading‐competent toxic α‐synuclein species

Jessica Tittelmeier, Carl Alexander Sandhof, H. Ries et al. · The EMBO Journal · 2020 · 82 citations · Full text