Role of G Protein–Coupled Receptor Kinases 2 and 3 in μ-Opioid Receptor Desensitization and Internalization

Anorexigenic and Orexigenic Hormone Modulation of Mammalian Target of Rapamycin Complex 1 Activity and the Regulation of Hypothalamic Agouti-Related Protein mRNA Expression

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Life Sciences, Endocrinology, Physiology +17

The selectivity of protein kinase inhibitors: a further update

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Medicine, Medicinal Chemistry, Pharmacology +14

An inhibitor of the protein kinases TBK1 and IKK-ɛ improves obesity-related metabolic dysfunctions in mice

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Life Sciences, Biochemistry, Physiology +12

Multiple pathways of rapid beta 2-adrenergic receptor desensitization. Delineation with specific inhibitors.

Martin J. Lohse, J.L. Benovic, M G Caron et al. · Journal of Biological Chemistry · 1990 · 398 citations · Full text

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An operational model of pharmacological agonism: the effect of E/[A] curve shape on agonist dissociation constant estimation

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