Author

Charles Chavkin

Byers, Margaret R, C CHAVKIN, C Chavkin, C. Chavkin, CHARLES CHAVKIN, Charles C Chavkin, Charles Chavkin, Preclinical studies have demonstrated the role of stress-induced dynorphin release in mediating a component of the anxiogenic and aversive effects of stress exposure. These results suggest that kappa opioid receptor (KOR) antagonists or low efficacy partial agonists may promote stress-resilience in humans and may potentially be useful in treating certain forms of mood disorders exacerbated by stressful experience. In rodent models