Concepedia

Involvement of FLIP in 2-Methoxyestradiol–Induced Tumor Regression in Transgenic Adenocarcinoma of Mouse Prostate Model

Manonmani Ganapathy, Rita Ghosh, Jianping Xie, Xiaoping Zhang, Roble Bedolla, John Schoolfield, I‐Tien Yeh, Dean A. Troyer, Aria F. Olumi, Addanki P. Kumar

Clinical Cancer Research · 2009 · 39 citations · 43 references

DOIFull text

Open access

Abstract

Targeting Sp1-mediated FLIP signaling pathway may provide a novel approach for prostate cancer management.

References

43

Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade

Peng Li, Deepak Nijhawan, I. Imawati Budihardjo et al. · Cell · 1997 · 7.2K citations · Full text

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Inhibition of death receptor signals by cellular FLIP

Martin Irmler, Margot Thome, Michael Hahne et al. · Nature · 1997 · 2.6K citations · Full text

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TRANSFAC(R): transcriptional regulation, from patterns to profiles

Volker Matys · Nucleic Acids Research · 2003 · 2K citations · Full text

The E3 Ubiquitin Ligase Itch Couples JNK Activation to TNFα-induced Cell Death by Inducing c-FLIPL Turnover

Lufen Chang, Hideaki Kamata, Giovanni Solinas et al. · Cell · 2006 · 687 citations · Full text

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Betulinic Acid Inhibits Prostate Cancer Growth through Inhibition of Specificity Protein Transcription Factors

Sudhakar Chintharlapalli, Sabitha Papineni, Shashi K. Ramaiah et al. · Cancer Research · 2007 · 296 citations · Full text