Endomysial and Tissue Transglutaminase Antibodies in Coeliac Sera: a Comparison not Influenced by Previous Serological Testing

Abstract

This study is the first to compare TTA with EMA. Due to 100% specificity and high sensitivity, EMA seems to be the most accurate coeliac antibody. Conversely, TTA offer advantages in terms of sensitivity and simplicity. A satisfactory strategy is to use TTA first and then EMA to confirm the borderline results.