Effects of fatty acid unsaturation numbers on membrane fluidity and α-secretase-dependent amyloid precursor protein processing

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Amyloidogenic processing of the Alzheimer β-amyloid precursor protein depends on lipid rafts

Robert Ehehalt, Patrick Keller, Christian Haass et al. · The Journal of Cell Biology · 2003 · 1.1K citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

BACE1 is the major β-secretase for generation of Aβ peptides by neurons

Huaibin Cai, Yanshu Wang, Diane B. McCarthy et al. · Nature Neuroscience · 2001 · 1.1K citations

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Reactive microglia in patients with senile dementia of the Alzheimer type are positive for the histocompatibility glycoprotein HLA-DR

Patrick L. McGeer, Shigeru Itagaki, Hisao Tago et al. · Neuroscience Letters · 1987 · 836 citations

Life Sciences, Immunology, Neuroscience +14

Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the β-amyloid precursor protein

Mark P. Mattson, Bin Cheng, Alan R. Culwell et al. · Neuron · 1993 · 799 citations

Life Sciences, Neurobiology, Neuroscience +16