CDK2 and mTOR are direct molecular targets of isoangustone A in the suppression of human prostate cancer cell growth

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<i>PTEN</i> , a Putative Protein Tyrosine Phosphatase Gene Mutated in Human Brain, Breast, and Prostate Cancer

Jing Li, Clifford Yen, Danny Liaw et al. · Science · 1997 · 4.8K citations

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Mice Lacking p27 Display Increased Body Size, Multiple Organ Hyperplasia, Retinal Dysplasia, and Pituitary Tumors

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Medicine, Endocrinology, Oncology +17

Enhanced Growth of Mice Lacking the Cyclin-Dependent Kinase Inhibitor Function of p27

Hiroaki Kiyokawa, Rhonda D. Kineman, Katia Manova‐Todorova et al. · Cell · 1996 · 1.3K citations · Full text

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Prostate-specific deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer

Shunyou Wang, Jing Gao, Qun‐Ying Lei et al. · Cancer Cell · 2003 · 1.1K citations · Full text

Medicine, Molecular Genetics, Oncology +15