Kangdong Liu

Unraveling the complexity of STAT3 in cancer: molecular understanding and drug discovery

Yamei Hu, Zigang Dong, Kangdong Liu · Journal of Experimental & Clinical Cancer Research · 2024 · 170 citations · Full text

Erianin suppresses constitutive activation of MAPK signaling pathway by inhibition of CRAF and MEK1/2

Penglei Wang, Xuechao Jia, Bingbing Lu et al. · Signal Transduction and Targeted Therapy · 2023 · 87 citations · Full text

SHAFTS: A Hybrid Approach for 3D Molecular Similarity Calculation. 2. Prospective Case Study in the Discovery of Diverse p90 Ribosomal S6 Protein Kinase 2 Inhibitors To Suppress Cell Migration

Weiqiang Lü, Xiaofeng Liu, Xianwen Cao et al. · Journal of Medicinal Chemistry · 2011 · 79 citations · Full text

Drug Target, Hit Identification, Structural Bioinformatics +22

Phosphorylation of Caspase-7 by p21-activated Protein Kinase (PAK) 2 Inhibits Chemotherapeutic Drug-induced Apoptosis of Breast Cancer Cell Lines

Xiang Li, Weihong Wen, Kangdong Liu et al. · Journal of Biological Chemistry · 2011 · 79 citations · Full text

Breast Oncology, Oncology, Pak Family +15

Targeting AKT with Oridonin Inhibits Growth of Esophageal Squamous Cell Carcinoma <i>In Vitro</i> and Patient-Derived Xenografts <i>In Vivo</i>

Mengqiu Song, Xuejiao Liu, Kangdong Liu et al. · Molecular Cancer Therapeutics · 2018 · 79 citations · Full text