Wedelolactone protects human bronchial epithelial cell injury against cigarette smoke extract-induced oxidant stress and inflammation responses through Nrf2 pathway

Annual report to the nation on the status of cancer, 1975–2004, featuring cancer in American Indians and Alaska Natives

David K. Espey, Xiao‐Cheng Wu, Judith Swan et al. · Cancer · 2007 · 583 citations

Medicine, Oncology, Population Health Sciences +17

Cyclooxygenase-2 overexpression is a marker of poor prognosis in stage I non-small cell lung cancer.

Fadlo R. Khuri, Hong Wu, B L Kemp et al. · PubMed · 2001 · 412 citations

Medicine, Cancer Biology, Carcinogenesis +11

Role of Nrf2 signaling in regulation of antioxidants and phase 2 enzymes in cardiac fibroblasts: Protection against reactive oxygen and nitrogen species‐induced cell injury

Hong Zhu, Ken Itoh, Masayuki Yamamoto et al. · FEBS Letters · 2005 · 389 citations

Life Sciences, Cell Biology, Physiology +17

Luteolin inhibits Nrf2 leading to negative regulation of the Nrf2/ARE pathway and sensitization of human lung carcinoma A549 cells to therapeutic drugs

Xiuwen Tang, Hongyan Wang, Longfang Fan et al. · Free Radical Biology and Medicine · 2011 · 322 citations

Medicine, Oncology, Pharmacology +13

Identification of retinoic acid as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha

Xiu Jun Wang, John D. Hayes, Colin J. Henderson et al. · Proceedings of the National Academy of Sciences · 2007 · 303 citations · Full text

Medicine, Cancer Biology, Pharmacology +16