Concepedia

Stattic: A Small-Molecule Inhibitor of STAT3 Activation and Dimerization

Jochen Schust, Bianca Sperl, Angela Hollis, Thomas U. Mayer, Thorsten Berg

Chemistry & Biology · 2006 · 1.1K citations · 39 references

DOI

Concepts

References

39

Anticancer potential of curcumin: preclinical and clinical studies.

Bharat B. Aggarwal, Anushree Kumar, Alok C. Bharti · PubMed · 2003 · 2.6K citations

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Constitutive Activation of Stat3 Signaling Confers Resistance to Apoptosis in Human U266 Myeloma Cells

Robyn Catlett-Falcone, Terry H. Landowski, Marc M. Oshiro et al. · Immunity · 1999 · 1.7K citations · Full text

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Three-dimensional structure of the Stat3β homodimer bound to DNA

Stefan Becker, Bernd Groner, Christoph W. Müller · Nature · 1998 · 792 citations

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Stat proteins and oncogenesis

Jacqueline Bromberg · Journal of Clinical Investigation · 2002 · 678 citations

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Discovery of JSI-124 (cucurbitacin I), a selective Janus kinase/signal transducer and activator of transcription 3 signaling pathway inhibitor with potent antitumor activity against human and murine cancer cells in mice.

Michelle A. Blaskovich, Jiazhi Sun, Alan Cantor et al. · PubMed · 2003 · 569 citations

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