A Conditionally Immortalized Epithelial Cell Line for Studies of Intestinal Drug Transport

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

Christopher A. Lipinski, Franco Lombardo, Beryl W. Dominy et al. · Advanced Drug Delivery Reviews · 1997 · 11.2K citations

Pharmacy, Pharmacokinetics, Pharmacology +16

Methods of enzymatic analysis

International Journal of Biochemistry · 1985 · 3.5K citations

Life Sciences, Biochemistry, Analytical Chemistry +11

Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells

Per Artursson, Johan Karlsson · Biochemical and Biophysical Research Communications · 1991 · 1.9K citations

Pharmacy, Pharmacokinetics, Pharmacology +16

Physiology of the Gastrointestinal Tract

Ann Ouyang · JAMA · 1988 · 969 citations

Life Sciences, Anatomy, Physiology +12

Epithelial Transport Of Drugs In Cell Culture. I: A Model For Studying The Passive Diffusion Of Drugs Over Intestinal Absorbtive (Caco-2) Cells

Per Artursson · Journal of Pharmaceutical Sciences · 1990 · 836 citations · Full text

Pharmacy, Pharmaceutics, Pharmacology +17