Concepedia

Paracellular Permeation

Paracellular Permeation is a route of drug permeation involving the passive diffusion of substances through the intercellular spaces between adjacent epithelial or endothelial cells, distinguished from transcellular permeation by its traversal outside the cells and dependence on tight junction architecture and aqueous pore pathways.

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2017–2026

241

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FRACTURE FACES OF ZONULAE OCCLUDENTES FROM "TIGHT" AND "LEAKY" EPITHELIA

Philippa Claude, Daniel A. Goodenough · The Journal of Cell Biology · 1973 · 1.1K citations · Full text

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Functional dissociation of paracellular permeability and transepithelial electrical resistance and disruption of the apical-basolateral intramembrane diffusion barrier by expression of a mutant tight junction membrane protein.

María S. Balda, J. Andrew Whitney, Claudia Flores et al. · The Journal of Cell Biology · 1996 · 869 citations · Full text

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Claudin-2 expression induces cation-selective channels in tight junctions of epithelial cells

Salah Amasheh, Noga Meiri, Alfred H. Gitter et al. · Journal of Cell Science · 2002 · 808 citations

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A cell culture model of the blood-brain barrier.

Lee L. Rubin, Deborah E. Hall, Stephen Porter et al. · The Journal of Cell Biology · 1991 · 774 citations · Full text

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Vascular Endothelial Growth Factor Induces Rapid Phosphorylation of Tight Junction Proteins Occludin and Zonula Occluden 1

David A. Antonetti, Alistair J. Barber, Leigh Ann Hollinger et al. · Journal of Biological Chemistry · 1999 · 678 citations · Full text

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  1. MF
    Michael Fromm

    Charité - Universitätsmedizin Berlin, Germany

    22 publications · 2.9K citations

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  2. DG
    Dorothee Günzel

    Charité - Universitätsmedizin Berlin, Germany

    20 publications · 1.9K citations

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  3. SM
    Susanne M. Krug

    Charité - Universitätsmedizin Berlin, Germany

    17 publications · 1.6K citations

    17

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  4. AS
    Alan S.L. Yu

    University of Kansas Medical Center, United States

    17 publications · 1.5K citations

    17

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  5. GI
    George I. Gorodeski

    Case Western Reserve University, United States

    13 publications · 391 citations

    12

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  1. Charité - Universitätsmedizin Berlin

    Berlin, Germany

    29 h-index

    184 publications

    16.5K citations

  2. Harvard University

    Cambridge, United States

    24 h-index

    85 publications

    11.2K citations

  3. Inserm

    Paris, France

    23 h-index

    116 publications

    9.6K citations

  4. Brigham and Women's Hospital

    Boston, United States

    15 h-index

    54 publications

    4.9K citations

  5. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    15 h-index

    73 publications

    6.4K citations

  6. Uppsala University

    Uppsala, Sweden

    15 h-index

    53 publications

    4.4K citations

  7. University of Arizona

    Tucson, United States

    15 h-index

    70 publications

    7.5K citations

  8. University of Chicago

    Chicago, United States

    15 h-index

    83 publications

    11.6K citations

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  1. American Journal of Physiology-Cell Physiology

    46 publications · 2.7K citations

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  2. PLoS ONE

    31 publications · 1.9K citations

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  3. Journal of Biological Chemistry

    JBC · 25 publications · 4.4K citations

    23

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  4. PubMed

    Repository · 36 publications · 1.7K citations

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