Delivery of a Liposomal <b> <i>c-raf-1</i> </b> Antisense Oligonucleotide by Weekly Bolus Dosing in Patients with Advanced Solid Tumors - Concepedia

Concepedia

Publication | Open Access

Delivery of a Liposomal <b> <i>c-raf-1</i> </b> Antisense Oligonucleotide by Weekly Bolus Dosing in Patients with Advanced Solid Tumors

DOI Full Paper Access

91

Citations

25

References

2004

Year

Charles M. Rudin, John L. Marshall, Chao Huang, Hedy L. Kindler, Chuanbo Zhang, Deepak Kumar, Prafulla C. Gokhale, Joyce Steinberg, S. P. Wanaski, Usha N. Kasid,

Clinical Cancer Research

Abstract

Dose-independent hypersensitivity reactions and dose-dependent thrombocytopenia limited tolerance of LErafAON. Future clinical evaluation of this approach will depend on modification of the liposome composition.

References

	Year	Citations

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