Concepedia

Maximum Tolerated Effect

Maximum Tolerated Effect is a pharmacodynamic endpoint that denotes the greatest magnitude of a therapeutic or toxic response achievable without exceeding the predetermined safety limits of an anticancer drug regimen.

1.5K

Publications

99.7K

Citations

10.3K

Authors

1.9K

Institutions

Publications per year

2017–2026

211

Parents

Publications

1.5K

Gabapentin for the Symptomatic Treatment of Painful Neuropathy in Patients With Diabetes Mellitus<SUBTITLE>A Randomized Controlled Trial</SUBTITLE>

Miroslav Bačkonja · JAMA · 1998 · 1.5K citations

, , +17

Ceritinib in <i>ALK</i> -Rearranged Non–Small-Cell Lung Cancer

Alice T. Shaw, Dong-Wan Kim, Ranee Mehra et al. · New England Journal of Medicine · 2014 · 1.5K citations

, , +14

Dose escalation of a curcuminoid formulation

Christopher D. Lao, Mack T. Ruffin, Daniel P. Normolle et al. · BMC Complementary and Alternative Medicine · 2006 · 1.4K citations · Full text

, , +13

Morphine, Gabapentin, or Their Combination for Neuropathic Pain

Ian Gilron, Joan M. Bailey, Dongsheng Tu et al. · New England Journal of Medicine · 2005 · 1.1K citations · Full text

, , +17

Gemcitabine Plus<i>nab</i>-Paclitaxel Is an Active Regimen in Patients With Advanced Pancreatic Cancer: A Phase I/II Trial

Daniel D. Von Hoff, Ramesh K. Ramanathan, Mitesh J. Borad et al. · Journal of Clinical Oncology · 2011 · 1K citations · Full text

, , +12

1–5 of 1.5K

Authors

10.3K

  1. EK
    Eric K. Rowinsky

    The University of Texas at San Antonio Health Science Center, United States

    28 publications · 2.9K citations

    21

    h-index

  2. JH
    Jan H.M. Schellens

    The Netherlands Cancer Institute, Netherlands

    20 publications · 2.1K citations

    18

    h-index

  3. SM
    Susan M. Blaney

    Children's Cancer Center, United States

    18 publications · 1.6K citations

    17

    h-index

  4. HA
    Howard A. Burris

    Sarah Cannon, United States

    20 publications · 2.6K citations

    17

    h-index

  5. JM
    Joel M. Reid

    Mayo Clinic, United States

    17 publications · 1.1K citations

    16

    h-index

1–5 of 10.3K

Institutions

1.9K

  1. The University of Texas MD Anderson Cancer Center

    Houston, United States

    53 h-index

    680 publications

    71.1K citations

  2. Memorial Sloan Kettering Cancer Center

    New York, United States

    45 h-index

    345 publications

    42.9K citations

  3. National Cancer Institute

    Bethesda, United States

    43 h-index

    462 publications

    38K citations

  4. Dana-Farber Cancer Institute

    Boston, United States

    39 h-index

    331 publications

    27.5K citations

  5. Massachusetts General Hospital

    Boston, United States

    27 h-index

    143 publications

    11.4K citations

  6. National Institutes of Health

    Bethesda, United States

    27 h-index

    173 publications

    11.6K citations

  7. Duke Medical Center

    Durham, United States

    24 h-index

    185 publications

    15.2K citations

  8. Harvard University

    Cambridge, United States

    24 h-index

    104 publications

    5.9K citations

1–8 of 1.9K

Venues

  1. Journal of Clinical Oncology

    385 publications · 34.3K citations

    103

    h-index

  2. Clinical Cancer Research

    106 publications · 10.6K citations

    62

    h-index

  3. PubMed

    Repository · 160 publications · 9.4K citations

    55

    h-index

  4. British Journal of Cancer

    BJC · 60 publications · 3.2K citations

    34

    h-index

  5. Cancer

    64 publications · 3.2K citations

    33

    h-index

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