Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation

A Strong Candidate for the Breast and Ovarian Cancer Susceptibility Gene <i>BRCA1</i>

Yoshio Miki, Jeffrey Swensen, Donna Shattuck-Eidens et al. · Science · 1994 · 6.1K citations

Life Sciences, Genetics, Molecular Genetics +17

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

Lawrence A. Donehower, Michele Harvey, Betty L. Slagle et al. · Nature · 1992 · 4.7K citations

Medicine, Cancer Biology, Molecular Genetics +14

Association of BRCA1 with Rad51 in Mitotic and Meiotic Cells

Ralph Scully, Junjie Chen, Annemieke W. Plug et al. · Cell · 1997 · 1.5K citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Deletion of a DNA Polymerase β Gene Segment in T Cells Using Cell Type-Specific Gene Targeting

Hua Gu, Jamey D. Marth, Paul C. Orban et al. · Science · 1994 · 1.4K citations

Life Sciences, Genetics, Molecular Genetics +17

Rad51 protein involved in repair and recombination in S. cerevisiae is a RecA-like protein

Akira Shinohara, Hideyuki Ogawa, Tomoko Ogawa · Cell · 1992 · 1.3K citations

Life Sciences, Genetics, Molecular Biology +16