Concepedia

Biological effects of acrylamide after daily ingestion of various foods in comparison to water: A study in rats

Franz Berger, Julia Feld, Daniel Bertow, Gerhard Eisenbrand, Gert Fricker, Natalie Gerhardt, Karl‐Heinz Merz, Elke Richling, Matthias Baum

Molecular Nutrition & Food Research · 2010 · 35 citations · 51 references

DOI

Abstract

The results suggest AA at dietary intake levels, exceeding estimated human mean intake by a factor of at least 100 to become detoxified in Sprague-Dawley rats to a major extent through glutathione coupling.

References

51

A simple technique for quantitation of low levels of DNA damage in individual cells

Narendra P. Singh, Michael T. McCoy, Raymond R. Tice et al. · Experimental Cell Research · 1988 · 10.7K citations · Full text

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A Lifetime Oncogenicity Study in Rats with Acrylamide

Mary Lusky Friedman · Fundamental and Applied Toxicology · 1995 · 375 citations

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Role of Cytochrome P450 2E1 in the Metabolism of Acrylamide and Acrylonitrile in Mice

Susan Sumner, Timothy R. Fennell, Timothy A. Moore et al. · Chemical Research in Toxicology · 1999 · 345 citations

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Hemoglobin Adducts of Acrylamide and Acrylonitrile in Laboratory Workers, Smokers and Nonsmokers

Emma Bergmark · Chemical Research in Toxicology · 1997 · 302 citations

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DNA Adduct Formation from Acrylamide via Conversion To Glycidamide in Adult and Neonatal Mice

Gonçalo Gamboa da Costa, Mona I. Churchwell, Lynne Hamilton et al. · Chemical Research in Toxicology · 2003 · 274 citations