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Scalable signaling mediated by T cell antigen receptor–CD3 ITAMs ensures effective negative selection and prevents autoimmunity

Autoimmune DiseaseImmunologyImmune RegulationEffective Negative SelectionSelf-toleranceT Cell ImmunityCd4 T Cell ResponsesAutoimmunityTolerance InductionCellular Immune ResponsePrevents AutoimmunityMedicineCell BiologyCell SignalingRegulatory T Cell BiologyT Cell Biology