Concepedia

Cd3 Complex Signaling

CD3 Complex Signaling is a molecular signaling mechanism within the T cell activation pathway that comprises the transduction of antigen recognition signals from the T cell receptor (TCR) to the intracellular compartment through immunoreceptor tyrosine-based activation motifs (ITAMs) embedded in the CD3 subunits, thereby initiating downstream cascades essential for T cell effector functions.

359

Publications

24K

Citations

1.5K

Authors

458

Institutions

Publications per year

2017–2026

16

Parents

Publications

359

TCR Activation of Human T Cells Induces the Production of Exosomes Bearing the TCR/CD3/ζ Complex

Nicolas Blanchard, Danielle Lankar, Florence Faure et al. · The Journal of Immunology · 2002 · 653 citations

, , +17

T-Cell Proliferation Involving the CD28 Pathway Is Associated witH Cyclosporine-Resistant Interleukin 2 Gene Expression

Carl H. June, Jeffrey A. Ledbetter, Marjorie Gillespie et al. · Molecular and Cellular Biology · 1987 · 526 citations · Full text

, , +12

Antigen recognition by human T lymphocytes is linked to surface expression of the T3 molecular complex

Ellis L. Reinherz, Stefan Meuer, Kathleen A. Fitzgerald et al. · Cell · 1982 · 489 citations

, , +16

T Cell Antigen Receptor-Mediated Activation of Phospholipase C Requires Tyrosine Phosphorylation

Tomas Mustelin, K. Mark Coggeshall, Noah Isakov et al. · Science · 1990 · 462 citations

, , +17

Regulation of T Cell Receptor Activation by Dynamic Membrane Binding of the CD3ɛ Cytoplasmic Tyrosine-Based Motif

Chenqi Xu, Étienne Gagnon, Matthew E. Call et al. · Cell · 2008 · 445 citations · Full text

, , +15

1–5 of 359

Authors

1.5K

  1. BM
    Bernard MALISSEN

    Centre d’Immunologie de Marseille-Luminy, France

    10 publications · 1K citations

    10

    h-index

  2. BA
    Balbino Alarcón

    Centro de Biología Molecular Severo Ochoa, Spain

    9 publications · 619 citations

    9

    h-index

  3. CT
    Cox Terhorst

    Harvard University, United States

    9 publications · 434 citations

    9

    h-index

  4. DA
    Dario A.A. Vignali

    St. Jude Children's Research Hospital, United States

    9 publications · 971 citations

    9

    h-index

  5. JS
    Jaime Sancho

    Instituto de Parasitología y Biomedicina "López - Neyra", Spain

    7 publications · 353 citations

    7

    h-index

1–5 of 1.5K

Institutions

458

  1. Dana-Farber Cancer Institute

    Boston, United States

    20 h-index

    77 publications

    8.5K citations

  2. Inserm

    Paris, France

    20 h-index

    121 publications

    11.7K citations

  3. Harvard University

    Cambridge, United States

    19 h-index

    98 publications

    10.3K citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    16 h-index

    86 publications

    6.5K citations

  5. Howard Hughes Medical Institute

    Chevy Chase, United States

    14 h-index

    44 publications

    3.9K citations

  6. Centre d’Immunologie de Marseille-Luminy

    Marseille, France

    13 h-index

    74 publications

    7.1K citations

  7. Max Planck Institute of Immunobiology and Epigenetics

    Freiburg, Germany

    10 h-index

    44 publications

    1.1K citations

  8. Institute of Molecular and Clinical Ophthalmology Basel

    Basel, Switzerland

    9 h-index

    12 publications

    434 citations

1–8 of 458

Venues

  1. The Journal of Immunology

    JI · 91 publications · 6.5K citations

    44

    h-index

  2. Journal of Biological Chemistry

    JBC · 31 publications · 1.9K citations

    25

    h-index

  3. European Journal of Immunology

    EJI · 40 publications · 1.7K citations

    24

    h-index

  4. PubMed

    Repository · 20 publications · 575 citations

    17

    h-index

  5. The Journal of Experimental Medicine

    16 publications · 1.4K citations

    15

    h-index

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