Noah Isakov

ζ Phosphorylation Without ZAP-70 Activation Induced by TCR Antagonists or Partial Agonists

Joaquı́n Madrenas, Ronald L. Wange, Jennifer L. Wang et al. · Science · 1995 · 502 citations

Life Sciences, Immunology, Molecular Biology +17

T Cell Antigen Receptor-Mediated Activation of Phospholipase C Requires Tyrosine Phosphorylation

Tomas Mustelin, K. Mark Coggeshall, Noah Isakov et al. · Science · 1990 · 462 citations

Life Sciences, Cell Biology, Immunology +17

Molecular cloning and characterization of PKC theta, a novel member of the protein kinase C (PKC) gene family expressed predominantly in hematopoietic cells.

Gottfried Baier, David Telford, Leslie Giampa et al. · Journal of Biological Chemistry · 1993 · 305 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +8

ZAP-70 binding specificity to T cell receptor tyrosine-based activation motifs: the tandem SH2 domains of ZAP-70 bind distinct tyrosine-based activation motifs with varying affinity.

Noah Isakov, Ronald L. Wange, Wilson H. Burgess et al. · The Journal of Experimental Medicine · 1995 · 202 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

Inhibition of the c-Jun N-terminal Kinase/AP-1 and NF-κB Pathways by PICOT, a Novel Protein Kinase C-interacting Protein with a Thioredoxin Homology Domain

Stephan Witte, Martín Villalba, Kun Bi et al. · Journal of Biological Chemistry · 2000 · 188 citations · Full text

Life Sciences, Biochemistry, Immunology +17