Concepedia

5′-triphosphate-siRNA: turning gene silencing and Rig-I activation against melanoma

Hendrik Poeck, Robert Besch, Cornelius Maihoefer, Marcel Renn, Damiá Tormo, Svetlana Shulga Morskaya, Susanne Kirschnek, Evelyn Gaffal, Jennifer Landsberg, Johannes C. Hellmuth,

Nature Medicine · 2008 · 385 citations · 20 references

DOI

Concepts

References

20

The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

Mitsutoshi Yoneyama, Mika Kikuchi, Takashi Natsukawa et al. · Nature Immunology · 2004 · 3.9K citations

, , +16

Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

Hiroki Kato, Osamu Takeuchi, Shintaro Sato et al. · Nature · 2006 · 3.8K citations

, , +12

Innate Antiviral Responses by Means of TLR7-Mediated Recognition of Single-Stranded RNA

Sandra S. Diebold, Tsuneyasu Kaisho, Hiroaki Hemmi et al. · Science · 2004 · 3.4K citations

, , +17

Calreticulin exposure dictates the immunogenicity of cancer cell death

Michel Obéid, Antoine Tesnière, François Ghiringhelli et al. · Nature Medicine · 2006 · 3.1K citations

, , +14

IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction

Taro Kawai, Ken Takahashi, Shintaro Sato et al. · Nature Immunology · 2005 · 2.5K citations

, , +12