Johannes C. Hellmuth

Elevated levels of IL-6 and CRP predict the need for mechanical ventilation in COVID-19

Tobias Herold, Vindi Jurinović, Chiara Arnreich et al. · Journal of Allergy and Clinical Immunology · 2020 · 1.1K citations · Full text

Medicine, Immunology, Infectious Diseases +14

Immunothrombotic Dysregulation in COVID-19 Pneumonia Is Associated With Respiratory Failure and Coagulopathy

Leo Nicolai, Alexander Leunig, Sophia Brambs et al. · Circulation · 2020 · 572 citations · Full text

Veterinary Medicine, Infectious Diseases, Pathobiology +17

5′-triphosphate RNA requires base-paired structures to activate antiviral signaling via RIG-I

Andreas Schmidt, Tobias Schwerd, Wolfgang Hamm et al. · Proceedings of the National Academy of Sciences · 2009 · 391 citations · Full text

Life Sciences, Biology, Molecular Biology +15

5′-triphosphate-siRNA: turning gene silencing and Rig-I activation against melanoma

Hendrik Poeck, Robert Besch, Cornelius Maihoefer et al. · Nature Medicine · 2008 · 385 citations

Life Sciences, Molecular Biology, Oncology +13

Level of IL-6 predicts respiratory failure in hospitalized symptomatic COVID-19 patients

Tobias Herold, Vindi Jurinović, Chiara Arnreich et al. · medRxiv · 2020 · 171 citations · Full text

Medicine, Infectious Diseases, Internal Medicine +17