Regulation of inosine monophosphate dehydrogenase type I and type II isoforms in human lymphocytes

Characterization of human type I and type II IMP dehydrogenases.

Stephen F. Carr, Eva Papp, J. Wu et al. · Journal of Biological Chemistry · 1993 · 425 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

Structure and Mechanism of Inosine Monophosphate Dehydrogenase in Complex with the Immunosuppressant Mycophenolic Acid

Michael D. Sintchak, Mark Fleming, Olga Futer et al. · Cell · 1996 · 421 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +12

Lymphocyte‐Selective Cytostatic and Immunosuppressive Effects of Mycophenolic Acid in Vitro: Role of Deoxyguanosine Nucleotide Depletion

Elsie M. Eugui, Susan J. Almquist, Christian D. Muller et al. · Scandinavian Journal of Immunology · 1991 · 399 citations

Life Sciences, Immunology, Pharmacology +14

Two distinct cDNAs for human IMP dehydrogenase.

Yutaka Natsumeda, Shigeo Ohno, Hiroshi Kawasaki et al. · Journal of Biological Chemistry · 1990 · 262 citations · Full text

Life Sciences, Molecular Biology, Oncology +8

Broad-Spectrum Antiviral Activity of the IMP Dehydrogenase Inhibitor VX-497: a Comparison with Ribavirin and Demonstration of Antiviral Additivity with Alpha Interferon

William Markland, Thomas McQuaid, Jugnu Jain et al. · Antimicrobial Agents and Chemotherapy · 2000 · 255 citations

Medicine, Medicinal Chemistry, Pharmacology +17