Concepedia

Allosteric Inhibition of the Protein-Protein Interaction between the Leukemia-Associated Proteins Runx1 and CBFβ

Michael J. Gorczynski, Jolanta Grembecka, Yunpeng Zhou, Yali Kong, Liya Roudaia, Michael G. Douvas, Miki Newman, Izabela Bielnicka, Gwen Baber, Takeshi Corpora,

Chemistry & Biology · 2007 · 118 citations · 39 references

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39

DREIDING: a generic force field for molecular simulations

Stephen L. Mayo, Barry D. Olafson, William A. Goddard · The Journal of Physical Chemistry · 1990 · 6.5K citations

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Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells

Jialun Wang, Dongxiang Liu, Zhijia Zhang et al. · Proceedings of the National Academy of Sciences · 2000 · 1.2K citations

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Rational design and characterization of a Rac GTPase-specific small molecule inhibitor

Yuan Gao, J. Bradley Dickerson, Fukun Guo et al. · Proceedings of the National Academy of Sciences · 2004 · 1.1K citations · Full text

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LigandFit: a novel method for the shape-directed rapid docking of ligands to protein active sites

C. M. Venkatachalam, Xiaoman Jiang, Tom Oldfield et al. · Journal of Molecular Graphics and Modelling · 2002 · 995 citations

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The computer program LUDI: A new method for the de novo design of enzyme inhibitors

Hans-Joachim B�hm · Journal of Computer-Aided Molecular Design · 1992 · 845 citations

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