Concepedia

Allosteric Stability

Allosteric Stability is a theoretical construct in Stability Engineering that denotes the capacity of a biomolecular system to maintain functional resilience through conformational regulation at distal sites, distinguishing it from local or direct stabilization mechanisms.

22

Publications

854

Citations

126

Authors

47

Institutions

Publications per year

2017–2026

7

Parents

Publications

22

Allosteric Inhibition of the Protein-Protein Interaction between the Leukemia-Associated Proteins Runx1 and CBFβ

Michael J. Gorczynski, Jolanta Grembecka, Yunpeng Zhou et al. · Chemistry & Biology · 2007 · 118 citations · Full text

, , +15

Nuclear RNA Exosome at 3.1 Å Reveals Substrate Specificities, RNA Paths, and Allosteric Inhibition of Rrp44/Dis3

John C. Zinder, Elizabeth V. Wasmuth, Christopher D. Lima · Molecular Cell · 2016 · 92 citations · Full text

, , +16

Allosteric Modulation Balances Thermodynamic Stability and Restores Function of ΔF508 CFTR

Andrei A. Aleksandrov, Pradeep Kota, Liying Cui et al. · Journal of Molecular Biology · 2012 · 91 citations · Full text

, , +14

Thiophene antibacterials that allosterically stabilize DNA-cleavage complexes with DNA gyrase

Pan F. Chan, Thomas Germe, B.D. Bax et al. · Proceedings of the National Academy of Sciences · 2017 · 84 citations · Full text

, , +17

Conformational changes in the allosteric inhibition of muscle pyruvate kinase by phenylalanine

F.J. Kayne, Nicholas C. Price · Biochemistry · 1972 · 53 citations

, , +15

1–5 of 22

Authors

126

  1. AE
    Alexey E. Alekseev

    Mayo Clinic, United States

    1 publications · 91 citations

    1

    h-index

  2. AA
    Andrei A. Aleksandrov

    University of North Carolina at Chapel Hill, United States

    1 publications · 91 citations

    1

    h-index

  3. TJ
    Tim Jensen

    University of Southern Denmark, Denmark

    1 publications · 91 citations

    1

    h-index

  4. DS
    D.K. Stammers

    University of Oxford, United Kingdom

    1 publications · 12 citations

    1

    h-index

  5. RK
    Reema K. Thalji

    GlaxoSmithKline (United States), United States

    1 publications · 84 citations

    1

    h-index

1–5 of 126

Institutions

47

  1. Tri-Institutional PhD Program in Chemical Biology

    New York, United States

    1 h-index

    1 publications

    92 citations

  2. Aptuit (Italy)

    Verona, Italy

    1 h-index

    1 publications

    84 citations

  3. Mayo Clinic

    Rochester, United States

    1 h-index

    2 publications

    182 citations

  4. University of Virginia

    Charlottesville, United States

    1 h-index

    9 publications

    1.1K citations

  5. Georgia Institute of Technology

    Atlanta, United States

    1 h-index

    1 publications

    20 citations

  6. John Innes Centre

    Norwich, United Kingdom

    1 h-index

    2 publications

    168 citations

  7. University of Toledo

    Toledo, United States

    1 h-index

    1 publications

    40 citations

  8. Kettering University

    Flint, United States

    1 h-index

    3 publications

    276 citations

1–8 of 47

Venues

  1. Biochemistry

    4 publications · 176 citations

    4

    h-index

  2. Chemical Communications

    ChemComm · 2 publications · 39 citations

    2

    h-index

  3. Nature Communications

    2 publications · 44 citations

    2

    h-index

  4. Journal of Biological Chemistry

    JBC · 2 publications · 26 citations

    2

    h-index

  5. Journal of Molecular Biology

    JMB · 1 publications · 91 citations

    1

    h-index

1–5