Concepedia

Targeted disruption of the EZH2–EED complex inhibits EZH2-dependent cancer

Woojin Kim, Gregory H. Bird, Tobias Neff, Guoji Guo, Marc A. Kerenyi, Loren D. Walensky, Stuart H. Orkin

Nature Chemical Biology · 2013 · 331 citations · 48 references

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48

Identification of human brain tumour initiating cells

Sheila K. Singh, Cynthia Hawkins, Ian D. Clarke et al. · Nature · 2004 · 7.4K citations

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Role of Histone H3 Lysine 27 Methylation in Polycomb-Group Silencing

Ru Cao, Liangjun Wang, Hengbin Wang et al. · Science · 2002 · 3.8K citations

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The polycomb group protein EZH2 is involved in progression of prostate cancer

Sooryanarayana Varambally, Saravana M. Dhanasekaran, Ming Zhou et al. · Nature · 2002 · 2.7K citations · Full text

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EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations

Michael T. McCabe, Heidi M. Ott, Gopinath Ganji et al. · Nature · 2012 · 1.8K citations

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Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin

Ryan D. Morin, Nathalie A. Johnson, Tesa Severson et al. · Nature Genetics · 2010 · 1.6K citations · Full text

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