Inhibition of Cytochromes P450 by Antifungal Imidazole Derivatives

Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.

Tsutomu Shimada, Hiroshi Yamazaki, Mayumi Mimura et al. · Journal of Pharmacology and Experimental Therapeutics · 1994 · 2.8K citations

Medicine, Biochemistry, Pharmacology +15

Cytochrome P450 isoform inhibitors as a tool for the investigation of metabolic reactions catalyzed by human liver microsomes.

Martine Bourrié, Viviane Meunier, Yves Berger et al. · Journal of Pharmacology and Experimental Therapeutics · 1996 · 362 citations

Medicine, Biochemistry, Pharmacology +15

Differential selectivity of cytochrome P450 inhibitors against probe substrates in human and rat liver microsomes

Victoria A. Eagling, John Tjia, David Back · British Journal of Clinical Pharmacology · 1998 · 336 citations · Full text

Medicine, Pharmacology, Biochemical Pharmacology +14

Cytochrome P450TB (CYP2C): A major monooxygenase catalyzing diclofenac 4′-hydroxylation in human liver

T. Leemann, C. Transon, Pierre Dayer · Life Sciences · 1993 · 267 citations

Medicine, Pharmacokinetics, Pharmacology +17

Effects of imidazole derivatives on cytochromes P450 from human hepatocytes in primary culture

Manuelle Maurice, Lydiane Pichard, Martine Daujat‐Chavanieu et al. · The FASEB Journal · 1992 · 262 citations

Medicine, Pharmacology, Biochemical Pharmacology +16