Concepedia

T. Leemann

TL

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Publications

23

Citations

1.5K

H-Index

17

Active since

1985

Affiliations

University Hospital of Geneva(Current)

University of Geneva

University of Basel

T. Leemann is an author at University Hospital of Geneva specializing in medicine, pharmacology, and biochemistry.

Top concepts

Publications per year

1985–2001

23

Publications

23

Cytochrome P450TB (CYP2C): A major monooxygenase catalyzing diclofenac 4′-hydroxylation in human liver

T. Leemann, C. Transon, Pierre Dayer · Life Sciences · 1993 · 267 citations

, , +12

Bioactivation of the narcotic drug codeine in human liver is mediated by the polymorphic monooxygenase catalyzing debrisoquine 4-hydroxylation (cytochrome P-450 dbl/bufI)

Pierre Dayer, Jules Desmeules, T. Leemann et al. · Biochemical and Biophysical Research Communications · 1988 · 208 citations

, , +9

In vitro comparative inhibition profiles of major human drug metabolising cytochrome P450 isozymes (CYP2C9, CYP2D6 and CYP3A4) by HMG-CoA reductase inhibitors

C. Transon, T. Leemann, Pierre Dayer · European Journal of Clinical Pharmacology · 1996 · 173 citations

, , +10

Dextromethorphan O-demethylation in liver microsomes as a prototype reaction to monitor cytochrome P-450 db1 activity

Pierre Dayer, T. Leemann, Rita Striberni · Clinical Pharmacology & Therapeutics · 1989 · 115 citations

Single-dose quinidine treatment inhibits metoprolol oxidation in extensive metabolizers

T. Leemann, Pierre Dayer, Urs Meyer · European Journal of Clinical Pharmacology · 1986 · 112 citations

, , +7

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